Specific Function of the Met-Tyr-Trp Adduct Radical and Residues Arg-418 and Asp-137 in the Atypical Catalase Reaction of Catalase-Peroxidase KatG

DOI: 10.1074/jbc.m112.401208 Authors: Xiangbo Zhao, Abdelahad Khajo, Sanchez Jarrett, Javier Suárez, Yan Levitsky, Richard M. Burger, Andrzej A. Jarzęcki, Richard S. Magliozzo Abstract: Catalase activity of the dual-function heme enzyme catalase-peroxidase (KatG)...

Enhanced Oxidation of Antibiotics by Ferrate Mediated with Natural Organic Matter: Role of Phenolic Moieties

DOI: 10.1021/acs.est.3c03165 Authors: Binglin Guo, Junyue Wang, Krishnamoorthy Sathiyan, Xingmao Ma, Éric Lichtfouse, Ching‐Hua Huang, Virender K. Sharma Abstract: The increasing presence of antibiotics in water sources threatens public health and ecosystems. Various...

Spectroscopic Investigation of the Activation of a Chromium-Pyrrolyl Ethene Trimerization Catalyst

DOI: 10.1021/acscatal.8b03414 Authors: Bas Venderbosch, Jean‐Pierre H. Oudsen, Lukas A. Wolzak, David James Martin, Ties J. Korstanje, Moniek Tromp Abstract: 1-Hexene is an important α-olefin for polyethylene production and is produced from ethene. Recent developments...

Redox Properties of Human Endothelial Nitric-oxide Synthase Oxygenase and Reductase Domains Purified from Yeast Expression System

DOI: 10.1074/jbc.m209606200 Authors: Mei Du, Hui-Chun Yeh, Vladimír Berka, Lee-Ho Wang, Ah‐Lim Tsai Abstract: Characterization of the redox properties of endothelial nitric-oxide synthase (eNOS) is fundamental to understanding the complicated reaction mechanism of...

Kinetic and Spectroscopic Characterization of a Hydroperoxy Compound in the Reaction of Native Myoglobin with Hydrogen Peroxide

DOI: 10.1074/jbc.m210383200 Authors: Tsuyoshi Egawa, Shiro Yoshioka, Satoshi Takahashi, Hiroshi Hori, Shingo Nagano, Hideo Shimada, Koichiro Ishimori, Isao Morishima, Makoto Suematsu, Yuzuru Ishimura Abstract: The reaction of metmyoglobin with H2O2 was investigated in...

Unraveling the biocatalytic mechanism of dipeptide formation using QM/MM and stopped-flow kinetic experiments

DOI: 10.1016/j.foodchem.2026.148931 Authors: Srinivasan Vinju Vasudevan, Pattabiraman Krishnamurthi, Jung-Kul Lee Abstract: N/A

Oxoferryl-Porphyrin Radical Catalytic Intermediate in Cytochrome bd Oxidases Protects Cells from Formation of Reactive Oxygen Species

DOI: 10.1074/jbc.m111.333542 Authors: Angela Paulus, Sebastiaan Gijsbertus Hendrik Rossius, M. B. van Dijk, Simon de Vries Abstract: The quinol-linked cytochrome bd oxidases are terminal oxidases in respiration. These oxidases harbor a low spin heme b(558) that...

A radical route to making methane

DOI: 10.1126/science.352.6288.949-q Authors: Nicholas S. Wigginton Abstract: Enzyme Mechanisms Microorganisms are the main drivers of Earth’s methane cycle. The enzyme ultimately responsible for biological methane production has an ambiguous mechanism because it...

Structural insights into the role of iron–histidine bond cleavage in nitric oxide-induced activation of H-NOX gas sensor proteins

DOI: 10.1073/pnas.1416936111 Authors: Mark A. Herzik, R. Jonnalagadda, John Kuriyan, Michael A. Marletta Abstract: Heme-nitric oxide/oxygen (H-NOX) binding domains are a recently discovered family of heme-based gas sensor proteins that are conserved across eukaryotes...

Comparison of cobalt and manganese in the chemistry of water oxidation

DOI: 10.1016/j.ccr.2012.04.039 Authors: J. Gregory McAlpin, Troy A. Stich, William H. Casey, R. David Britt Abstract: N/A