Inner Ear and Muscle Developmental Defects in Smpx-Deficient Zebrafish Embryos

DOI: 10.3390/ijms22126497 Authors: Anna Ghilardi, Alberto Diana, Renato Bacchetta, Nadia Santo, Miriam Ascagni, Laura Prosperi, Luca Del Giacco Abstract: The last decade has witnessed the identification of several families affected by hereditary non-syndromic hearing...

Human nitrobindin: the first example of an all‐β‐barrel ferric heme‐protein that catalyzes peroxynitrite detoxification

DOI: 10.1002/2211-5463.12534 Authors: Giovanna De Simone, Alessandra di Masi, Fabio Polticelli, Paolo Ascenzi Abstract: Nitrobindins (Nbs), constituting a heme-protein family spanning from bacteria to Homo sapiens, display an all-β-barrel structural organization....

Novel anti-inflammatory properties of mannose oligosaccharides in the treatment of inflammatory bowel disease via LGALS3 modulation

DOI: 10.1038/s41522-025-00648-3 Authors: Yaqi Du, Yan Fan, Xin Li, Fenqin Chen Abstract: This study investigates the role of Gum Arabic Mannose Oligosaccharides (GA-MOS) in modulating gut microbiota and alleviating symptoms of Inflammatory Bowel Disease (IBD)....

Recent Advances on the Rational Design of Non-Precious Metal Oxide Catalysts Exemplified by CuOx/CeO2 Binary System: Implications of Size, Shape and Electronic Effects on Intrinsic Reactivity and Metal-Support Interactions

DOI: 10.3390/catal10020160 Authors: Michalis Konsolakis, Maria Lykaki Abstract: Catalysis is an indispensable part of our society, massively involved in numerous energy and environmental applications. Although, noble metals (NMs)-based catalysts are routinely employed...

Designed folding pathway of modular coiled-coil-based proteins

DOI: 10.1038/s41467-021-21185-5 Authors: Jana Aupič, Žiga Strmšek, Fabio Lapenta, David Pahovnik, Tomaž Pisanski, Igor Drobnak, Ajasja Ljubetič, Roman Jerala Abstract: Natural proteins are characterised by a complex folding pathway defined uniquely for each fold....