Synthesis and reactivity of the high-valent monomeric and dimeric manganese complexes.

DOI: OA:W3012417436 Authors: Wen‐Yuan Hsieh Abstract: Photosynthetic water oxidation to form dioxygen occurs using a manganese cluster in the oxygen evolving complex (OEC). The higher oxidation states (S3 and S4) of the Mn cluster are still unclear. To examine the...

Kinetic Characterization of Compound I Formation in the Thermostable Cytochrome P450 CYP119

DOI: 10.1074/jbc.c100745200 Authors: David Kellner, Shao-Ching Hung, Kara E. Weiss, Stephen G. Sligar Abstract: The kinetics of formation and breakdown of the putative active oxygenating intermediate in cytochrome P450, a ferryl-oxo-(pi) porphyrin cation radical...

Direct spectroscopic detection of a C-H-cleaving high-spin Fe(IV) complex in a prolyl-4-hydroxylase

DOI: 10.1073/pnas.0604005103 Authors: Lee M. Hoffart, Eric W. Barr, Robert B. Guyer, J. Martin Bollinger, Carsten Krebs Abstract: The Fe(II)- and alpha-ketoglutarate (alphaKG)-dependent dioxygenases use mononuclear nonheme iron centers to effect hydroxylation of their...

Evaluation of research and development: Methods for evaluating the results of European community R & D programmes

DOI: 10.1016/0377-2217(83)90273-4 Authors: Alok Chakrabarti Abstract: N/A

Vibrational analyses of the reaction of oxymyoglobin with NO using a photolabile caged NO donor at cryogenic temperatures

DOI: 10.1016/j.jinorgbio.2024.112633 Authors: Therese Albert, A. VInay Kumar, Jonathan D. Caranto, Pierre Moënne‐Loccoz Abstract: N/A

Replacing the Axial Ligand Tyrosine 75 or Its Hydrogen Bond Partner Histidine 83 Minimally Affects Hemin Acquisition by the Hemophore HasAp from Pseudomonas aeruginosa

DOI: 10.1021/bi500030p Authors: Ritesh Kumar, Hirotoshi Matsumura, Scott Lovell, Huili Yao, Juan Carlos Rodrı́guez, K.P. Battaile, Pierre Moënne‐Loccoz, Mario Rivera Abstract: Hemophores from Pseudomonas aeruginosa (HasAp), Serratia marcescens (HasAsm), and Yersinia...

Facile Electron Transfer during Formation of Cluster X and Kinetic Competence of X for Tyrosyl Radical Production in Protein R2 of Ribonucleotide Reductase from Mouse

DOI: 10.1021/bi011797p Authors: Danny Yun, Carsten Krebs, Govind P. Gupta, David F. Iwig, Boi Hanh Huynh, J. Martin Bollinger Abstract: The kinetics and mechanism of formation of the tyrosyl radical and mu-(oxo)diiron(III) cluster in the R2 subunit of ribonucleotide...

1.22 Rapid Mixing Techniques for the Study of Enzyme Catalysis

DOI: 10.1016/b978-0-12-374920-8.00127-2 Authors: Sandra Mitić, S. de Vries Abstract: N/A

Substrate Binding Is the Rate-limiting Step in Thromboxane Synthase Catalysis

DOI: 10.1074/jbc.m009177200 Authors: Lee-Ho Wang, Ah‐Lim Tsai, Pei-Yung Hsu Abstract: Thromboxane synthase (TXAS) is a « non-classical » cytochrome P450. Without any need for an external electron donor, or for a reductase or molecular oxygen, it uses prostaglandin H2...

Freeze‐Quench Kinetics

DOI: 10.1002/0470862106.ia340 Authors: Simon de Vries Abstract: Abstract Rapid‐mixing, rapid‐freezing techniques are employed for the study of enzyme or chemical catalytic mechanisms. The techniques aim to provide electronic and molecular structures of transient...