DOI:
Authors:
Walter Sandtner, Diethart Schmid, Klaus Schicker, Klaus Gerstbrein, Xaver Koenig, Felix P. Mayer, Stefan Boehm, Michael Freissmuth, Harald H. Sitte
Abstract:
This discrepancy in decay rates is inconsistent with the molecular stent hypothesis. In contrast, a multistate version of the alternative access model accounts for all the observations and reproduces the kinetic parameters extracted from the electrophysiological recordings. A crucial feature that explains the action of amphetamines is their lipophilic nature, which allows for rapid diffusion through the membrane.