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DOI:

10.1186/s13065-015-0103-6

Authors:

Grant J. Sherborne, Bao N. Nguyen

Abstract:

A brief review of studies using X-ray Absorption Spectroscopy (XAS) to investigate homogeneous catalytic reactions in fine chemical and pharmaceutical context since 2010 is presented. The advantages of the techniques over traditional lab-based analytical tools, particularly when NMR spectroscopy fails to deliver mechanistic insights, are summarised using these examples. A discussion on the current limitations of the techniques and challenges in the near future is also included. Graphical abstractA minireview of recent developments in application of X-ray Absorption Spectroscopy as an effective mechanistic tool to synthetic catalytic reactions relevant to fine chemical and pharmaceutical syntheses.