Prevalence of antibodies against a Sindbis-related (Pogosta) virus, a potential cause of chronic arthritis

DOI: 10.1186/ar503 Authors: Auli Toivanen, M. Laine, R Luukkainen, Jarmo Oksi, Raija Vainionpää Abstract: Vascular changes are consistent early findings in patients with SSc and often precede the development of fibrosis. Despite a significant reduction in the...

Anti-Ro/SSA antibodies in systemic sclerosis (SSc): determination of the fine specificity, clinical and laboratory correlations

DOI: 10.1186/ar527 Authors: Chiara M. Antonioli, Franco Franceschini, Ilaria Cavazzana, Paolo Airó, E Danieli, R Bettoni, Roberto Cattaneo Abstract: Vascular changes are consistent early findings in patients with SSc and often precede the development of fibrosis....

Sustainable Building Design

DOI: OA:W207343751 Authors: Peter Schmid Abstract: Humankind lives within (a part of) the manifested Universe. The planet earth with its resources is, beside the sun and some other exterresterial phenomena, the physical base of our life. In the last century, mainly...

Reshaping the shared epitope hypothesis: HLA-associated risk for rheumatoid arthritis is encoded by amino acid substitutions at position 67 to 74 of the HLA-DRB1 molecule

DOI: 10.1186/ar466 Authors: Niek de Vries, Henk Tijssen, Plcm van Riel, Lba van de Putte Abstract: Vascular changes are consistent early findings in patients with SSc and often precede the development of fibrosis. Despite a significant reduction in the capillary...

Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

DOI: 10.1172/jci5909 Authors: Zhou Zhu, Robert Homer, Zhonde Wang, Qingsheng Chen, Gregory P. Geba, Jingming Wang, Yong Zhang, Jack A. Elias Abstract: Interleukin (IL)-13 is a pleiotropic cytokine produced in large quantities by activated CD4(+) Th2 lymphocytes. To...