Oriented triplex DNA as a synthetic receptor for transmembrane signal transduction

DOI: 10.1038/s41467-024-53960-5 Authors: Hui Chen, Shaohong Zhou, Kleins Ngocho, Jing Zheng, Xiaoxiao He, Jin Huang, Kemin Wang, Hui Shi, Jianbo Liu Abstract: Signal transduction across biological membranes enables cells to detect and respond to diverse chemical or...

Anticytotoxin Effects of Amentoflavone to Pneumolysin

DOI: 10.1248/bpb.b16-00598 Authors: Xiaoran Zhao, Bowen Liu, Shui Liu, Lin Wang, Jianfeng Wang Abstract: Pneumolysin (PLY) is a devastating bacterial protein toxin of Streptococcus pneumoniae that punctures the cytomembrane, leading to pathological reactions, such as...

Preparation, Structural Characterization, and Stability of Low-Molecular-Weight Collagen Peptides–Calcium Chelate Derived from Tuna Bones

DOI: 10.3390/foods12183403 Authors: Yaqi Zhong, Yufang Zhou, Mingzhu Ma, Yadong Zhao, Xingwei Xiang, Cong-Han Shu, Bin Zheng Abstract: This study was conducted to prepare calcium chelate of low-molecular-weight tuna bone collagen peptides (TBCPLMW) with a high...

Engineering the protein dynamics of an ancestral luciferase

DOI: 10.1038/s41467-021-23450-z Authors: Andrea Schenkmayerová, Gaspar Pinto, Martin Toul, Martin Marek, Lenka Hernychová, Joan Planas-Iglesias, Veronika Lišková, Daniel Pluskal, Michal Vasina, Stéphane Emond, Mark Dörr, Radka Chaloupková, David Bednář, Zbyněk Prokop,...

Cyclic Ruthenium-Peptide Conjugates as Integrin-Targeting Phototherapeutic Prodrugs for the Treatment of Brain Tumors

DOI: 10.1021/jacs.3c04855 Authors: Liyan Zhang, Peiyuan Wang, Xue‐Quan Zhou, Ludovic Bretin, Xiaolong Zeng, Yurii Husiev, Ehider A. Polanco, Gangyin Zhao, Lukas S. Wijaya, Tarita Biver, Sylvia E. Le Dévédec, Wen Sun, Sylvestre Bonnet Abstract: To investigate the...