Alterations in ventricular K_ATPchannel properties during aging

DOI: 10.1111/acel.12033 Authors: Bao Li, Eylem Taşkın, Monique Foster, Beevash Ray, Rosa Rosario, Radha Ananthakrishnan, Susan E. Howlett, Ann Marie Schmidt, Ravichandran Ramasamy, William A. Coetzee Abstract: Coronary heart disease remains the principle cause of...

Subunit Arrangement in P2X Receptors

DOI: 10.1523/jneurosci.23-26-08903.2003 Authors: Lin‐Hua Jiang, Miran Kim, Valeria Spelta, Xuenong Bo, Annmarie Surprenant, R. Alan North Abstract: ATP-gated ionotropic receptors (P2X receptors) are distributed widely in the nervous system. For example, a...

Microglial amyloid beta clearance is driven by PIEZO1 channels

DOI: 10.1186/s12974-022-02486-y Authors: Henna Jäntti, Valeriia Sitnikova, Yevheniia Ishchenko, Anastasia Shakirzyanova, Luca Giudice, Irene F. Ugidos, Mireia Gómez‐Budia, Nea Korvenlaita, Sohvi Ohtonen, Irina Belaya, Mohammad Feroze Fazaludeen, Nikita Mikhailov,...

Structure of the receptor-activated human TRPC6 and TRPC3 ion channels

DOI: 10.1038/s41422-018-0038-2 Authors: Qinglin Tang, Wenjun Guo, Zheng Li, Jing-Xiang Wu, Meng Liu, Xindi Zhou, Xiaolin Zhang, Lei Chen Abstract: N/A

Sulfonylurea receptors set the maximal open probability, ATP sensitivity and plasma membrane density of K_ATP channels

DOI: 10.1016/s0014-5793(99)00102-7 Authors: Andrey P. Babenko, Gabriela González, Lydia Aguilar‐Bryan, Joseph Bryan Abstract: KATP channels are heteromultimers of SUR and KIR6.2. C-terminal truncation of KIR6.2 allows surface expression of the pore. KIR6.2deltaC35...