Reactive Intermediates in Cytochrome P450 Catalysis

DOI: 10.1074/jbc.r113.473108 Authors: Courtney M. Krest, Elizabeth L. Onderko, Timothy H. Yosca, Julio C. Calixto, Richard Karp, Jovan Livada, Jonathan Rittle, Michael T. Green Abstract: Recently, we reported the spectroscopic and kinetic characterizations of...

Cyanide inhibition of cytochrome c oxidase. A rapid-freeze e.p.r. investigation

DOI: 10.1042/bj2240829 Authors: P. Jensen, Michael T. Wilson, Roland Aasa, Bo G. Malmström Abstract: The inhibition of cytochrome c oxidase by cyanide, starting either with the resting or the pulsed enzyme, was studied by rapid-freeze quenching followed by...

Enzymatic Birch Reduction via Hydrogen Atom Transfer at an Aqua-Tungsten-bis-Metallopterin Cofactor

DOI: 10.1021/acscatal.3c01781 Authors: Carola S. Seelmann, Simona G. Huwiler, Martin Culka, Marc J. F. Strampraad, Till Biskup, Stefan Weber, G. Matthias Ullmann, Volker Schünemann, Peter‐Leon Hagedoorn, Antonio J. Pierik, Matthias Boll Abstract: The Birch reduction...

Reversible amorphization and the catalytically active state of crystalline Co3O4 during oxygen evolution

DOI: 10.1038/ncomms9625 Authors: Arno Bergmann, Elías Martínez-Moreno, Detre Teschner, Petko Chernev, Manuel Gliech, Jorge Ferreira de Araújo, Tobias Reier, Holger Dau, Peter Strasser Abstract: Water splitting catalysed by earth-abundant materials is pivotal for...

Probing substrate binding to the metal binding sites in metallo-β-lactamase L1 during catalysis

DOI: 10.1039/c5md00358j Authors: Mahesh Aitha, Sameer Al-Adbul-Wahid, David L. Tierney, Michael W. Crowder Abstract: Metal ions in metallo-β-lactamases (MBLs) play a major role in catalysis. In this study we investigated the role of the metal ions in the Zn1 and Zn2...