Mechanism of Assembly of the Dimanganese-Tyrosyl Radical Cofactor of Class Ib Ribonucleotide Reductase: Enzymatic Generation of Superoxide Is Required for Tyrosine Oxidation via a Mn(III)Mn(IV) Intermediate

DOI: 10.1021/ja312457t Authors: Joseph A. Cotruvo, Troy A. Stich, R. David Britt, JoAnne Stubbe Abstract: Ribonucleotide reductases (RNRs) utilize radical chemistry to reduce nucleotides to deoxynucleotides in all organisms. In the class Ia and Ib RNRs, this reaction...

The pathway of electrons through QH2:cytochrome c oxidoreductase studied by pre-steady-state kinetics

DOI: 10.1016/0005-2728(82)90276-6 Authors: S. de Vries, Simon P. J. Albracht, J.A. Berden, E.C. Slater Abstract: N/A

Insights in the mechanism of selective olefin oligomerisation catalysis using stopped-flow freeze-quench techniques: A Mo K-edge QEXAFS study

DOI: 10.1016/j.jcat.2011.10.015 Authors: Stuart A. Bartlett, Peter P. Wells, Maarten Nachtegaal, Andrew J. Dent, Giannantonio Cibin, Gillian Reid, John Evans, Moniek Tromp Abstract: N/A

Kinetic analysis of amino acid radicals formed in H ₂ O ₂ -driven Cu ^I LPMO reoxidation implicates dominant homolytic reactivity

DOI: 10.1073/pnas.1922499117 Authors: Stephen M. Jones, Wesley J. Transue, Katlyn K. Meier, Bradley R. Kelemen, Edward I. Solomon Abstract: Lytic polysaccharide monooxygenases (LPMOs) have been proposed to react with both [Formula: see text] and [Formula: see text] as...

Cobamides and Ribonucleotide Reduction

DOI: 10.1016/s0021-9258(19)42735-x Authors: William H. Orme‐Johnson, Helmut Beinert, Raymond L. Blakley Abstract: Abstract Reaction mixtures containing coenzyme B12 (5′-deoxyadenosylcobalamin), an equivalent concentration of ribonucleotide reductase from...