Reduction and Oxidation of the Active Site Iron in Tyrosine Hydroxylase:  Kinetics and Specificity

DOI: 10.1021/bi052283j Authors: Patrick A. Frantom, Javier Seravalli, Stephen W. Ragsdale, Paul F. Fitzpatrick Abstract: Tyrosine hydroxylase (TyrH) is a pterin-dependent enzyme that catalyzes the hydroxylation of tyrosine to form dihydroxyphenylalanine. The oxidation...

A Hot Oxidant, 3-NO₂Y₁₂₂ Radical, Unmasks Conformational Gating in Ribonucleotide Reductase

DOI: 10.1021/ja1069344 Authors: Kenichi Yokoyama, Ulla Uhlin, JoAnne Stubbe Abstract: Escherichia coli ribonucleotide reductase is an α2β2 complex that catalyzes the conversion of nucleotides to deoxynucleotides and requires a diferric-tyrosyl radical (Y(•)) cofactor...

EPR and Infrared Spectroscopic Evidence That a Kinetically Competent Paramagnetic Intermediate is Formed When Acetyl-Coenzyme A Synthase Reacts with CO

DOI: 10.1021/ja0528329 Authors: Simon J. George, Javier Seravalli, Stephen W. Ragsdale Abstract: Carbon monoxide dehydrogenase/acetyl-CoA synthase (CODH/ACS) is a bifunctional enzyme which enables archaea and bacteria to grow autotrophically on CO and hydrogen/carbon...

Conformational equilibria and dynamics of cytochrome c induced by binding of sodium dodecyl sulfate monomers and micelles

DOI: 10.1007/s00249-003-0306-y Authors: Silke Oellerich, Hainer Wackerbarth, Peter Hildebrandt Abstract: N/A

Activation of [CrCl₃{R-SN(H)S-R}] Catalysts for Selective Trimerization of Ethene: A Freeze-Quench Cr K-Edge XAFS Study

DOI: 10.1021/cs501017g Authors: Stuart A. Bartlett, Jerome Moulin, Moniek Tromp, Gillian Reid, Andrew J. Dent, Giannantonio Cibin, David S. McGuinness, John Evans Abstract: Homogeneous chromium catalysts for the selective conversion of ethene to hex-1-ene are formed...