Decarboxylation involving a ferryl, propionate, and a tyrosyl group in a radical relay yields heme b

DOI: 10.1074/jbc.ra117.000830 Authors: Bennett R. Streit, Arianna I. Celis, Garrett C. Moraski, Krista A. Shisler, Eric M. Shepard, Kenton R. Rodgers, Gudrun S. Lukat-Rodgers, Jennifer L. DuBois Abstract: The H2O2-dependent oxidative decarboxylation of coproheme III...

Use of Noncanonical Tyrosine Analogues to Probe Control of Radical Intermediates during Endoperoxide Installation by Verruculogen Synthase (FtmOx1)

DOI: 10.1021/acscatal.2c01037 Authors: Chi‐Yun Lin, Angel L. Muñoz Hernández, Tatiana N. Laremore, Alexey Silakov, Carsten Krebs, Amie K. Boal, J. Martin Bollinger Abstract: Important bioactive natural products, including prostaglandin H2 and artemisinin, contain...

The Mechanisms of Catalysis by Metallo β‐Lactamases

DOI: 10.1155/2008/576297 Authors: Michael I. Page, Adriana Badarau Abstract: Class B beta-lactamases or metallo-beta-lactamases (MBLs) require zinc ions to catalyse the hydrolysis of beta-lactam antibiotics such as penicillins, cephalosporins, carbapenems, and...

On-grid and in-flow mixing for time-resolved cryo-EM

DOI: 10.1107/s2059798321008810 Authors: David P. Klebl, Howard D. White, Frank Sobott, Stephen P. Muench Abstract: Time-resolved cryo-electron microscopy (TrEM) allows the study of proteins under non-equilibrium conditions on the millisecond timescale, permitting the...

EPR of Short-Lived Magnetic Species

DOI: 10.1007/978-3-030-39668-8_10 Authors: Vincent Maurel, S. Gambarelli Abstract: N/A