The Kinetic Reaction Mechanism of the Vibrio cholerae Sodium-dependent NADH Dehydrogenase

DOI: 10.1074/jbc.m115.658773 Authors: Karina Tuz, Katherine G. Mezic, Tianhao Xu, Blanca Barquera, Oscar Juárez Abstract: The sodium-dependent NADH dehydrogenase (Na(+)-NQR) is the main ion transporter in Vibrio cholerae. Its activity is linked to the operation of the...

Advanced X-ray absorption spectroscopy : Analyzing electronic structures of catalysts

DOI: OA:W3021031383 Authors: Jean‐Pierre H. Oudsen Abstract: In catalysis, it is important to know the exact structure of the catalyst, especially under catalytic conditions. Spectroscopic information on the catalyst is crucial to reveal for example structure-activity...

The Reaction of Trimethylamine Dehydrogenase with Trimethylamine

DOI: 10.1074/jbc.274.19.13147 Authors: Mei-Huei Jang, Jaswir Basran, Nigel S. Scrutton, Russ Hille Abstract: The reductive half-reaction of trimethylamine dehydrogenase has been studied using the substrate diethylmethylamine over the pH range 6-10. It is found that...

Detection, identification, and quantification of oxidative protein modifications

DOI: 10.1074/jbc.rev119.006217 Authors: Clare L. Hawkins, Michael J. Davies Abstract: Exposure of biological molecules to oxidants is inevitable and therefore commonplace. Oxidative stress in cells arises from both external agents and endogenous processes that...

Antibiotic Resistance in Mycobacterium tuberculosis

DOI: 10.1074/jbc.m109.005546 Authors: Javier Suárez, Kalina Ranguelova, Johannes P. M. Schelvis, Richard S. Magliozzo Abstract: KatG (catalase-peroxidase) in Mycobacterium tuberculosis is responsible for activation of isoniazid (INH), a pro-drug used to treat...