Induction of Th2 cell differentiation by cognate interaction of CD4 memory T cells

DOI: 10.1186/ar513 Authors: Alla Skapenko, PE Lipsky, JR Kalden, Hendrik Schulze‐Koops Abstract: Vascular changes are consistent early findings in patients with SSc and often precede the development of fibrosis. Despite a significant reduction in the capillary...

Deregulated Ras and Rap1 signaling in rheumatoid arthritis T cells leads to persistent production of free radicals

DOI: 10.1186/ar495 Authors: PHJ Remans, KA Reedquist, Bos Jl, CL Verweij, FC Breedveld, JM van Laar, Sonja I. Gringhuis Abstract: Vascular changes are consistent early findings in patients with SSc and often precede the development of fibrosis. Despite a significant...

<title>The Display-Stereocomparator, A New Device For Biostereometric Measurements</title>

DOI: 10.1117/12.956923 Authors: E. Hierholzer Abstract: The display stereocomparator, which was primarily designed for the evaluation of stereoradiographs, is quite similar to the common stereocomparator, except that the usual point-shaped target is replaced by a...

HMGB1 is a potent proinflammatory mediator expressed abundantly in chronic synovitis

DOI: 10.1186/ar480 Authors: UG Andersson, Helena Erlandsson Harris, Riikka Kokkola, Erik Sundberg, A-K Ulfgren, Karin Palmblad Abstract: Vascular changes are consistent early findings in patients with SSc and often precede the development of fibrosis. Despite a...

Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

DOI: 10.1172/jci5909 Authors: Zhou Zhu, Robert Homer, Zhonde Wang, Qingsheng Chen, Gregory P. Geba, Jingming Wang, Yong Zhang, Jack A. Elias Abstract: Interleukin (IL)-13 is a pleiotropic cytokine produced in large quantities by activated CD4(+) Th2 lymphocytes. To...