Decarboxylation involving a ferryl, propionate, and a tyrosyl group in a radical relay yields heme b

DOI: 10.1074/jbc.ra117.000830 Authors: Bennett R. Streit, Arianna I. Celis, Garrett C. Moraski, Krista A. Shisler, Eric M. Shepard, Kenton R. Rodgers, Gudrun S. Lukat-Rodgers, Jennifer L. DuBois Abstract: The H2O2-dependent oxidative decarboxylation of coproheme III...

Horseradish Peroxidase Phe172→ Tyr Mutant

DOI: 10.1074/jbc.270.31.18413 Authors: Vaughn P. Miller, David B. Goodin, Alan E. Friedman, Christa Hartmann, Paul R. Ortiz de Montellano Abstract: A gene coding for the F172Y mutant of horseradish peroxidase isozyme C (HRP) has been constructed and expressed in both...

Comparison of cobalt and manganese in the chemistry of water oxidation

DOI: 10.1016/j.ccr.2012.04.039 Authors: J. Gregory McAlpin, Troy A. Stich, William H. Casey, R. David Britt Abstract: N/A

Structural insights into the role of iron–histidine bond cleavage in nitric oxide-induced activation of H-NOX gas sensor proteins

DOI: 10.1073/pnas.1416936111 Authors: Mark A. Herzik, R. Jonnalagadda, John Kuriyan, Michael A. Marletta Abstract: Heme-nitric oxide/oxygen (H-NOX) binding domains are a recently discovered family of heme-based gas sensor proteins that are conserved across eukaryotes...

A radical route to making methane

DOI: 10.1126/science.352.6288.949-q Authors: Nicholas S. Wigginton Abstract: Enzyme Mechanisms Microorganisms are the main drivers of Earth’s methane cycle. The enzyme ultimately responsible for biological methane production has an ambiguous mechanism because it...