Replacing Arginine 33 for Alanine in the Hemophore HasA from Pseudomonas aeruginosa Causes Closure of the H32 Loop in the Apo-Protein

DOI: 10.1021/acs.biochem.6b00239 Authors: Ritesh Kumar, Yifei Qi, Hirotoshi Matsumura, Scott Lovell, Huili Yao, K.P. Battaile, Wonpil Im, Pierre Moënne‐Loccoz, Mario Rivera Abstract: Previous characterization of hemophores from Serratia marcescens (HasAs), Pseudomonas...

Three Aromatic Residues are Required for Electron Transfer during Iron Mineralization in Bacterioferritin

DOI: 10.1002/anie.201507486 Authors: Justin M. Bradley, Dimitri A. Svistunenko, T. Lawson, Andrew M. Hemmings, Geoffrey R. Moore, Nick E. Le Brun Abstract: Ferritins are iron storage proteins that overcome the problems of toxicity and poor bioavailability of iron by...

Peroxidase Self-inactivation in Prostaglandin H Synthase-1 Pretreated with Cyclooxygenase Inhibitors or Substituted with Mangano Protoporphyrin IX

DOI: 10.1074/jbc.m100628200 Authors: Gang Wu, Jennifer L. Vuletich, Richard J. Kulmacz, Yoichi Osawa, Ah-Lim Tsai Abstract: Self-inactivation imposes an upper limit on bioactive prostanoid synthesis by prostaglandin H synthase (PGHS). Inactivation of PGHS peroxidase...

STRUCTURE/FUNCTION STUDIES ON METALLO-B- LACTAMASE ImiS FROM Aeromonas bv. sobria

DOI: OA:W2597859157 Authors: Narayan Prasad Sharma Abstract: Zinc-containing metallo–lactamases(MLs) are an emerging class of enzymes that render bacteria resistant to -lactam-containing antibiotics, and these enzymes have been grouped into 3 distinct classes,...

Structure and activity of ChiX: a peptidoglycan hydrolase required for chitinase secretion by Serratia marcescens

DOI: 10.1042/bcj20170633 Authors: Richard A. Owen, Paul K. Fyfe, Adam Lodge, Jacob Biboy, Waldemar Vollmer, William N. Hunter, Frank Sargent Abstract: The Gram-negative bacterium Serratia marcescens secretes many proteins that are involved in extracellular chitin...