RETRACTED ARTICLE: Endoperoxide formation by an α-ketoglutarate-dependent mononuclear non-haem iron enzyme

DOI: 10.1038/nature15519 Authors: Wupeng Yan, Heng Song, Fuhang Song, Yisong Guo, Cheng-Hsuan Wu, Ampon Sae Her, Yi Pu, Shu Wang, Nathchar Naowarojna, Andrew C. Weitz, Michael P. Hendrich, Catherine E. Costello, Lixin Zhang, Pinghua Liu, Yan Zhang Abstract:...

Trapping and Characterization of a Reaction Intermediate in Carbapenem Hydrolysis by B. cereus Metallo-β-lactamase

DOI: 10.1021/ja801169j Authors: Mariana F. Tioni, Leticia I. Llarrull, Andrés A. Poeylaut-Palena, Marcelo A. Martí, Miguel Saggu, Gopal R. Periyannan, Ernesto G. Mata, Brian Bennett, Daniel H. Murgida, Alejandro J. Vila Abstract: Metallo-beta-lactamases hydrolyze most...

Mechanism of Assembly of the Tyrosyl Radical-Dinuclear Iron Cluster Cofactor of Ribonucleotide Reductase

DOI: 10.1126/science.1650033 Authors: J. Martin Bollinger, Dale E. Edmondson, B.H. Huynh, Jonathan Filley, Jack R. Norton, J. Stubbe Abstract: Incubation of the apoB2 subunit of Escherichia coli ribonucleotide reductase with Fe2+ and O2 produces native B2, which...

Probing the Reaction Mechanism of the d-ala-d-ala Dipeptidase, VanX, by Using Stopped-Flow Kinetic and Rapid-Freeze Quench EPR Studies on the Co(II)-Substituted Enzyme

DOI: 10.1021/ja0627343 Authors: Megan L. Matthews, Gopalraj Periyannan, Christine E. Hajdin, Tara K. Sidgel, Brian Bennett, Michael W. Crowder Abstract: In an effort to probe the reaction mechanism of VanX, the d-ala-d-ala dipeptidase required for high-level...

The Ferroxidase Reaction of Ferritin Reveals a Diferric μ-1,2 Bridging Peroxide Intermediate in Common with Other O₂-Activating Non-Heme Diiron Proteins

DOI: 10.1021/bi990095l Authors: Pierre Moënne‐Loccoz, Carsten Krebs, Kara Herlihy, Dale E. Edmondson, Elizabeth C. Theil, Boi Hanh Huynh, Thomas M. Loehr Abstract: Ferritins are ubiquitous proteins that concentrate, store, and detoxify intracellular iron through...