High drug-loading gold nanoclusters for responsive glucose control in type 1 diabetes

DOI: 10.1186/s12951-019-0505-z Authors: Yujie Zhang, Mingxin Wu, Wubin Dai, Min Chen, Zhaoyang Guo, Xin Wang, Di Tan, Kui Shi, Longjian Xue, Sheng Liu, Yifeng Lei Abstract: We successfully developed a phenylboronic acid-functionalized gold nanocluster system...

Comprehensive investigation of a dye-decolorizing peroxidase and a manganese peroxidase from Irpex lacteus F17, a lignin-degrading basidiomycete

DOI: 10.1186/s13568-018-0648-6 Authors: Zihong Duan, Rui Shen, Binjie Liu, Mengwei Yao, Rong Jia Abstract: Irpex lacteus F17 is well-known for its ability to degrade recalcitrant aromatic pollutants, which mainly results from the action of the manganese peroxidase...

Single-droplet surface-enhanced Raman scattering decodes the molecular determinants of liquid-liquid phase separation

DOI: 10.1038/s41467-022-32143-0 Authors: Anamika Avni, Ashish Joshi, Anuja Walimbe, Swastik G. Pattanashetty, Samrat Mukhopadhyay Abstract: Biomolecular condensates formed via liquid-liquid phase separation (LLPS) are involved in a myriad of critical cellular...

Cell surface binding, uptaking and anticancer activity of L-K6, a lysine/leucine-rich peptide, on human breast cancer MCF-7 cells

DOI: 10.1038/s41598-017-08963-2 Authors: Che Wang, Shaodan Dong, Lin Zhang, Ying Zhao, Lili Huang, Xian-Ge Gong, He Wang, Dejing Shang Abstract: Cell surface binding and internalization are critical for the specific targeting and biofunctions of some cationic...

Aptamer-functionalized nanoscale metal-organic frameworks for targeted photodynamic therapy

DOI: 10.7150/thno.26768 Authors: Hong‐Min Meng, Xiaoxiao Hu, Gezhi Kong, Chan Yang, Ting Fu, Zhaohui Li, Xiaobing Zhang Abstract: Photodynamic therapy (PDT) has been applied in clinical cancer treatment. Here we report an aptamer-functionalized nanoscale metal-organic...