RIP2 filament formation is required for NOD2 dependent NF-κB signalling

DOI: 10.1038/s41467-018-06451-3 Authors: Erika Pellegrini, Ambroise Desfosses, Arndt Wallmann, Wiebke Manuela Schulze, Kristina Rehbein, Philippe J. Mas, Luca Signor, Gaudon Stephanie, Grasilda Zenkevičiūtė, Michael Hons, Hélène Malet, Irina Gutsche, Carsten Sachse,...

Author response: Allosteric signalling in the outer membrane translocation domain of PapC usher

DOI: 10.7554/elife.03532.020 Authors: Irene Farabella, Thieng Pham, Nadine S. Henderson, Sebastian Geibel, Gilles Phan, David G. Thanassi, Anne H. Delcour, Gabriel Waksman, Maya Topf Abstract: Full text Figures and data Side by side Abstract eLife digest Introduction...

Polyvariant mutant cystic fibrosis transmembrane conductance regulator genes. The polymorphic (Tg)m locus explains the partial penetrance of the T5 polymorphism as a disease mutation.

DOI: 10.1172/jci639 Authors: Harry Cuppens, Wen‐chang Lin, Martine Jaspers, Bruno Costes, H Teng, Anne Vankeerberghen, Mark Jorissen, G. Droogmans, Ingrid Reynaert, M. Goossens, Bernd Nilius, J.J. Cassiman Abstract: In congenital bilateral absence of the vas deferens...

The RootScope: a simple high-throughput screening system for quantitating gene expression dynamics in plant roots

DOI: 10.1186/1471-2229-13-158 Authors: Erin J Kast, Minh-Duyen T Nguyen, Rosalie Lawrence, Christina Rabeler, Nicholas J. Kaplinsky Abstract: The RootScope system is a simple and powerful platform for investigating the heat shock response in...

Acting on the CFTR Membrane-Spanning Domains Interface Rescues Some Misfolded Mutants

DOI: 10.3390/ijms232416225 Authors: Nesrine Baatallah, Ahmad Elbahnsi, B. Chevalier, Solène Castanier, Jean‐Paul Mornon, Iwona Pranke, Aleksander Edelman, Isabelle Sermet‐Gaudelus, Isabelle Callebaut, Alexandre Hinzpeter Abstract: ABC transporters are large membrane...